If you mean you have multiple Scalix servers and you want to route all Internet Mail to the Scalix server in the data centre from where it goes out to the internet, then this is possible.
By default, when you install scalix, the internet mail gateway is setup with a mailnode of "internet", together with a TNEF variant "internet,tnef".
You can see these routes either by running:
omshowux
or
omshowrt -q unix
On the spoke machine, all you need to do is "re-direct" the "internet" route to the Scalix server in the data centre, and provided the Internet Mail gateway on the data centre server is configured with the mailnode "internet" the message will go out (or at least be given to sendmail for onward processing).
To do this, run:
omdelrt -m "internet"
this deletes the existing route.
omaddrt -m "internet" -q smintfc -i
scalix@fqdn.of.data.centre.host
when a message is sent to an internet address on this server, the message will now route to the data centre machine for onward processing.
This is a little like the smart host ability of sendmail.
You should repeat the commands for the mailnode "internet,tnef" if required.
I don't understand the last part of your question, in terms of primary and backup email server. I'f I've mis-read your requirement please re-post. If you want primary and backup routes then I think you could achieve this using MX records such that if one server is down the secondary MX host will be tried.
Hope that helps.
Cheers,
JG