I have upgraded our server to V 11.4.6 over the holiday. Now users with Windows Vista and Windows7 (with latest IE 8 ) popup blocker will not allow SWA to open up even if they specifically add the server IP address to the popup blocker to allow settings via Tools/popup blocker settings.
When I connect with GoToAssist remote desktop support, it auto_magically works!

I don't have a Vista or Win7 test computer so I can't test it myself (cheap IT department).
Any suggestions?